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Dr Michael  Menze

Dr Michael Menze

Associate Professor

Office: 2029 - Life Science
Phone: 217-581-6386
Email: mmenze@eiu.edu
Website: http://ux1.eiu.edu/~mmenze/

Michael Menze's Vita

My lab focuses on the biochemical underpinnings of adaptations to extreme environmental insults such as elevated temperatures, severe desiccation, and freezing in animals. Undergraduate and graduate students are highly encouraged to contact me by phone or email about current research opportunities. For more information and manuscripts please see:

http://works.bepress.com/michael_menze/

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Speakers Bureau

For more information, please visit the Speakers Bureau Webpage.

Engaging undergraduate students in inquiry-based research experiences

Selected Publications

Selected Publications
 
Martinez E., Menze M.A., Hendricks* E., and Torres J.J. (2015) Physiological performance of warm-adapted marine ectotherms: thermal limits of mitochondrial energy transduction efficiency. Comp. Biochem. Physiol. Ain press.

Martinez E., Porreca* A.P., Colombo R.E. and Menze M.A. (2015) Tradeoffs of warm adaptation in aquatic ectotherms: live fast, die young? Comp. Biochem. Physiol. A, in press.

Hand S.C. and Menze M.A. (2015).  Molecular approaches for improving desiccation tolerance: insights from the brine shrimp Artemia franciscana. Planta 242(2):379-388.

Stokich B., Osgood Q., Grimm D., Moorthy S., Chakraborty N., and Menze M.A. (2014). Cryopreservation of hepatocyte (HepG2) cell monolayers: impact of trehalose. Cryobiology 69(2):281-90.

Roberts M.E., Crail J.P., Laffoon M., Fernandez W., Menze M.A., and Konkle M.E. (2013). Identification of disulfide bond formation between mitoNEET and glutamate dehydrogenase 1. Biochemistry 52 (50): 8969-8971.

Martinez# E., Menze# M.A., and Torres J.J. (2013). Mitochondrial energetics of benthic and pelagic Antarctic teleosts. Mar. Biol. 160: 2813-2823.

Marunde M.A., Samarajeewa* D.A., Anderson* J., Li S., Hand S.C., and Menze M.A. (2013). Improved tolerance to salt and water stress in Drosophila melanogaster cells conferred by late embryogenesis abundant protein. J. Insect. Physiol. 59: 377-386.

Li S., Chakraborty N., Borcar A., Menze M.A., Toner M., Hand S.C. (2012). Late embryogenesis abundant proteins protect human hepatoma cells during acute desiccation. Proc. Natl. Acad. Sci. U. S. A. 109 (51): 20859-64.

Hand S.C, Menze M.A., Toner M, Boswell L., and Moore D. (2011). Expression of LEA proteins during water stress: not just for plants anymore. Annu. Rev. Physiol. 17 (73):115-34.

Menze M.A., Boswell L., Toner M. and Hand S.C. (2009). Occurrence of mitochondrial-targeted late embryogenesis abundant (LEA) gene in animals increases organelle resistance to water stress. J. Biol. Chem. 284 (16): 10714-10719.

*EIU graduate student researcher,undergraduate student researcher underlined.
#Authors contributed equally

Selected Conference Presentations

Selected Presentations

Grimm D.F., Altamirano L, Paudel* S., Welker L., Herrera J., Konkle M., and Menze M.A. Effects of pioglitazone on liver cell bioenergetics. Presented at the annual meeting of the American Society for Cell Biology (ASCB), Philadelphia, PA, 2014.

Paudel* S., Welker L., Nathan B.P., Konkle M. and Menze MA. D-galactose decreases mitoNEET (CISD1) levels in HepG2 cells. Presented at the annual meeting of the American Society for Cell Biology (ASCB), Philadelphia, PA, 2014.

Stokich B. and Menze M.A. Biomimetic approaches in cryopreservation. Presented at the annual meeting of the American Society for the Advancement in Sciences (AAAS), Chicago, IL, 2014.

Fernandez W., Erbacher L., Konkle M., and Menze M.A. Examining the role of estrogen and oxidative damage in Alzheimer's Disease. Posters on the Hill. To highlight undergraduate research to U.S. Senators and Representatives. Capitol Hill, Washington, DC, 2013.

Martinez E., Menze M.A., and Torres J.J. Mitochondrial energetics of benthic and pelagic Antarctic teleosts. Presented at the annual meeting of the American Society of Limnology and Oceanography, New Orleans, LA, 2013.

Camp N., Martinez E., Phillips C., Procerra*  A., Torres J., Colombo R., and Menze M.A. Life in hot waters: live fast and die young. Presented at the annual meeting of the Society for Integrative and Comparative Biology (SICB). San Francisco, CA, 2013.

Marunde M., Nguyen M.A., Hand S.C., and Menze M.A. Late Embryogenesis Abundant protein improves mitochondrial function under salt and water stress.  Presented at the annual meeting of the Society for Integrative and Comparative Biology (SICB). San Francisco, CA, 2013.

Menze M.A. Group I LEA protein ameliorates inhibition of mitochondrial respiration in Drosophila Kc167 cells. Presented at the annual Mitochondrial Physiology (MIP) meeting, Obergurgl, Austria, 2013.


*EIU graduate student researcher,undergraduate student researcher underlined.

Funding & Grants

NSF grant “Collaborative Research: Mechanisms of Tolerance to Severe Water Stress in Animals“ (05/2015 - 04/2019; Michael Menze, PI; IOS-1456809). Amount awarded: $173,373.

NSF grant “Mechanisms of Animal Desiccation Tolerance” (09/2009 - 09/2014; Steven Hand, PI, Michael Menze, Co-PI; IOS-0920254). Total amount awarded: $600,000. To investigate the increase in dehydration tolerance of transgenic Drosophila cell lines that is conferred by late embryogenesis abundant proteins (LEA) from the brine shrimp Artemia franciscana.

Antarctic Expedition “Collaborative Research: Possible Climate Induced Changes in the Distribution of Pleuragramma antarcticum on the Western Antarctic Peninsula Shelf” (03/10-05/10; Jose Torres, PI, Michal Menze, Participating Faculty,B-258-N). To investigate the impact of temperature on mitochondrial function in P. antarcticum.


Awards in Teaching 
 
2015 Student Government Distinguished Faculty Award.
2014 Provost's Undergraduate Research Mentor Award.
2013 College of Sciences Lida G. Wall Faculty Research Mentor and Teacher Award.
2012 College of Sciences Student Advisory Board Outstanding Faculty Teaching Award.

Awards in Research
 
2013 Achievement and Contribution Award.
2011 Achievement and Contribution Award.
2011 Deans Award of Excellence in Research and Creative Activity.
2010 Deans Award of Excellence in Research and Creative Activity.


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