Our current research attempts are the preparation of host molecules with a cavity and their ability of encapsulation and release of smaller guests could be controlled by an external input toward design of controllable chemical delivery agents, devices and sensors. By using a combination of hydrogen bonding, aromatic stacking, and coordination, etc., we expect to produce stable host-guest complexes with predictable chemical properties.
It is essential in supramolecular chemistry to have a deep understanding upon molecular recognition, to study the traficking of substrates, then to study the effects of encapsulation toward chemical reactivity and selectivity.
Zhiqing Yan, Shijing Xia, Matthew Gardlik, Wanji Seo, Veselin Maslak, Judith Gallucci, and Jovica D. Badjić, “Silver(I) mediated folding of a molecular basket,” Org. Lett. 2007, 9(12), 2301-2304.
Zhiqing Yan, Yuning Chang, Dennis Mayo, Veselin Maslak, Shijing Xia, and Jovica D. Badjić, “Allosteric regulation of the conformational dynamics of a cavitand receptor,” Org. Lett. 2006, 8(17), 3697-3700.
Veselin Maslak, Zhiqing Yan, Shijing Xia, Judith Gallucci, Christopher M. Hadad, and Jovica D. Badjić, “Design, synthesis and conformational dynamics of a gated molecular basket,” J. Am. Chem. Soc. 2006, 128, 5887-5894.
Veselin Maslak, Zhiqing Yan, and Jovica D. Badjić, “Trifluorovinyllithium” In “Encyclopedia of Reagents for Organic Synthesis,” John Wiley and Sons Ltd., UK, 2005.